While the parotid and submandibular glands have been reported as predominant sites for oncocytic mec omec, the palate and minor salivary glands are rare sites for occurrence. Oncocytes in mucoepidermoid carcinoma of the palate. Mucoepidermoid carcinoma of the jaw is a rare tumour of unknown aetiology. A case of an unusual tumor of the palate is presented, in which the differential diagnosis focusses on either adenoid cystic carcinoma with squamous metaplasia or a basaloid. Presents as painless, slowgrowing mass that is firm or hard. Nov 02, 2014 mucoepidermoid carcinomas mecs of minor salivary gland origin are rare in children and adolescents and have been reported rarely. Only one had radiographic evidence of bony invasion and was treated by composite resection of the hard palate. However it can present in the minor salivary glands, especially in the soft palate.
A 45yearold man presented to the clinic with a years history of a painless growth on the right side of the palate. Mucoepidermoid carcinoma mec, first described by masson and berger in 1924, is a wellrecognized salivary gland neoplasm, accounting for 510% of all salivary gland tumors. Mucoepidermoid carcinoma of the soft palate salivary gland. The aim of this study was to investigate retrospectively a bonesparing approach to resection of low grade mucoepidermoid carcinoma of the hard palate in 18 patients. Patil vidyapeeth, pimpri, pune, maharashtra, india. I had very clear margins, however, as a precaution i will also be undergoing radiation in a couple of weeks. Herein is present a case of a malignant myoepithelioma arising in the hard palate of a 79yearold woman. Apr 18, 2019 the palate is divided anatomically into the hard palate part of the oral cavity and the soft palate part of the oropharynx. Management of mucoepidermoid carcinoma of the palate. Ive been told margins were free and i dont need any radiation or chemio. We report the case of a 72yearold malay female after presentation with sore throat, fever and odynophagia, was diagnosed with mucoepidermoid carcinoma of the soft palate.
It occurs almost exclusively in the intraoral minor salivary glands and represents less than 1% of all salivary gland tumors. Internet search disclosed cases reported from several countries. Mucoepidermoid carcinoma can also be found in other organs, such as bronchi, lacrimal sac, and thyroid gland. Although about a 100 cases has been reported in literature, the speculation on its. A rare case report article pdf available in journal of indian society of periodontology 202 january 2015 with 203 reads how we measure reads.
Mucoepidermoid carcinoma mec is the epithelial salivary gland neoplasm of the oral cavity. Epithelialmyoepithelial carcinoma of the hard palate. We report a case of an adult male who presented with a mucoepidermoid carcinoma involving the minor salivary glands of the palate at age 57 years, followed by an adenoid cystic carcinoma of the floor of mouth at age 63 years. Primary myoepithelial carcinoma of palate world journal of. Global journal of otolaryngology issn 24747556 the palate. Myoepitheliomas are tumors arising from myoepithelial cells mainly or exclusively. Primary clear cell carcinoma of minor salivary gland of the. Mar 18, 2019 a retrospective study by aro et al found that in patients with salivary gland cancer who underwent curativeintent local resection and neck dissection with a minimum of 10 lymph nodes removed, those who were treated with postoperative radiotherapy had a better 5year overall survival rate 67. Mucicarmine staining is one stain used by pathologist for detection. Salivary gland tumors are clinically diverse group of neoplasms, of which pleomorphic adenoma and mucoepidermoid carcinoma mec are most common benign and malignant tumors, respectively. Aug 14, 2019 mucoepidermoid carcinoma in children appears to follow a more favorable course with cure rates of 98100% ord 1994.
Besides the major salivary glands, these tumors can affect the minor salivary gland tissues in the posterior part of the hard palate. The palate is divided anatomically into the hard palate part of the oral cavity and the soft palate part of the oropharynx. Central mucoepidermoid carcinoma cmc is an uncommon tumor, comprising 23 % of all mucoepidermoid carcinomas reported. Mucoepidermoid carcinoma of the palate in a child article pdf available in pediatric dentistry 224. Salivary gland tumors usually occur as single lesions. Cancer of the soft palate accounts for approximately 2% of head and neck mucosal malignancies. Mucoepidermoid carcinoma of palate a rare entity ncbi. Mucoepidermoid carcinoma definition of mucoepidermoid. Mucoepidermoid carcinoma of the palate in a 5yearold girl. Oral squamous cell carcinoma of palate a case report and.
Oral cancer, squamous cell carcinoma, young patients. Cancer in young patients part 2 oral cancers in lowrisk subjects. Polymorphous lowgrade adenocarcinoma plga is a rare, asymptomatic, slowgrowing malignant salivary gland tumor. Pdf mucoepidermoid carcinoma of the palate in a 5yearold. Mucoepidermoid carcinoma involving the palate with lamellated calcifications. It has a slight female predilection and usually presents as a painless, rubberlike or soft mass, which may be fixed or mobile. Kulkarni, lakshmi shetty, vishal zurange department of oral and maxillofacial surgery, dr. Epithelial neoplasms originating in the minor salivary glands account for approximately 15% of all salivary gland neoplasms 6, 38. Epithelialmyoepithelial carcinoma of the hard palate a najihah 1, my mohd razif,mr isa 2,mn jabar 3,sha primuharsa putra 1 1 department of otorhinolaryngologyhead and neck surgery, university kebangsaan.
Whereas, mucoepidermoid carcinoma of high grade malignancy strongly resembles squamous cell carcinoma. Cancer of the oral cavity is mostly trigger by smoking, alcohol abuse. A case report k a saleh, mrcs entglasg, nurishmah md. Central mucoepidermoid carcinoma of mandible a case report. Mec frequently involves the major salivary glands and is rarely seen involving the jaws. We report a case of mucoepidermoid carcinoma mec in the palate of a 43yearold female that exhibited a prominent oncocytic component. The earliest signs of a mucoepidermoid carcinoma may include a lump in the face, neck, or mouth. Sclerosing mucoepidermoid carcinoma of the parotid. The majority of cases occurring in the 4th and 5th decades of life and they are histologically lowgrade malignant neoplasm usually affecting the mandible. Pdf mucoepidermoid carcinoma of the palate in a 5year. One percent of head and neck malignant neoplasms and 10% of salivary gland neoplasms are adenoid cystic carcinomas acc. Is it necessary to resect bone for lowgrade mucoepidermoid.
Mucoepidermoid carcinomas mec of minor salivary gland origin are rare in children and adolescents. It markedly responded to both radiotherapy and chemotherapy. Mucoepidermoid carcinoma genetic and rare diseases. Surgical treatment of the mucoepidermoid carcinoma of minor salivary gland origin is primarily a function of the anatomic site of the tumor and its histologic grade. Joseph dental college, duggirala, eluru, andhra pradesh, india. Mucoepidermoid carcinoma is the most common type of minor salivary gland malignancy in adults.
It has a varied microscopic architectural appearance, i. Management of the neck and regional recurrence in squamous cell. Minor salivary gland tumors med oral patol oral cir bucal. Most common salivary gland type tumor in the lung, tends to arise centrally similar morphology to mucoepidermoid carcinoma arising in the head and neck with a mixture of mucous cells, squamous cells and intermediate cells. Adenoid cystic carcinoma of the palate with squamous. Oral cavity, hard palate, surgical intervention, carcinoma, neoplasm. The study of hard palate squamous cell carcinoma has been mentioned in research publications which can be found using our bioinformatics tool below. Aug 12, 2014 minor salivary gland tumors in children are uncommon. Treatment often begins with surgery to remove the entire tumor.
Mucoepidermoid carcinoma of hard palate gill s, mohan a. Mar 26, 2018 mucoepidermoid carcinoma soft palate malignant epithelial salivary gland neoplasm 10% of all salivary tumors, 30% of all salivary malignancies about 30% of these tumors arise from the minor salivary glands in the buccal mucosa and soft palate, the rest from major salivary glands arises from ductal epithelium, has both epidermoid and mucinous components appearance. Adenoid cystic carcinoma in palate and maxillary sinus scielo. Mucoepidermoid carcinoma abstract the mucoepidermoid carcinoma of the palate is an uncommon disease. Pdf mucoepidermoid carcinoma of the palate in a child. Myoepitheliomas mostly occur in salivary glands, as well as in breast, skin, and lung. Mucoepidermoid carcinoma palate low grade help cancer. Primary central mucoepidermoid carcinoma of jaws is a rare lesion comprising 23% of all mucoepidermoid carcinomas reported in literature. Management of mucoepidermoid carcinoma of the palate utilizing ffdg petct year. Minor salivary gland mucoepidermoid carcinoma in children and. A notable finding anuradha ananthaneni, haripriya ponnapalli, mohammad asif kiresur, sv krishna chaitanya department of oral and maxillofacial pathology, st.
Mucoepidermoid carcinoma involving the palate with lamellated. Unusual epithelialmyoepithelial carcinoma in palate case. The lesion had been examined by biopsy at another hospital, and diagnosed as a poorly differentiated squamous cell carcinoma. The purpose of this case report is to discuss the clinical manifestation, diagnosis, and treatment plan of mec of the palate. Introduction epithelialmyoepithelial carcinoma emc is defined by the world health organization who classification in 1991 as a rare lowgrade malignant neoplasm and account for than 1% of salivary glands tumors 1,2. The lesion was initially the size of a peanut and had gradually enlarged to attain the present size of 3 cm.
It is nonaggressive when compared to other oral cavity. Had a surgery 20 days ago to remove a lump on my right palate 1. Clinically and pathologically, the low grade malignant mucoepidermoid carcinoma closely resembles pleomorphic adenoma. Basal cell adenocarcinoma of the palate with squamous. The case presented is a 41 year old woman with central mucoepidermoid carcinoma at the left posterior of the mandible.
Mucoepidermoid carcinoma soft palate rads iowa head and. We hope that this case report will contribute to the enlightenment of the behavior and prognosis of pediatric mec of palatal minor salivary. Recently, a case of mucoepidermoid carcinoma of the hard palate was experienced. Mucoepidermoid carcinoma mec is the most common primary salivary gland malignancy in both adults and children. Mucoepidermoid carcinoma of minor salivary gland in buccal. Literature regarding their clinical features and biologic behavior is scanty. Two cases of mucoepidermoid carcinoma of the parotid gland associated with extensive central sclerosis and peripheral lymphoid response are reported.
Occasional focal sebaceous cells, goblet type cells, oncocytic change, inflammatory reaction to extravasated mucin or keratin. Hccc is a new and rare lowgrade salivary gland neoplasm which occurs in the primary clear cell carcinoma of minor salivary gland of the soft palate. Basal cell adenocarcinoma is a rare salivary gland tumour, especially in minor glands. My first biopsy said it was low grade, but post surgery they told me it was intermediate grade. It has been estimated that about 1% to 5% of all salivary gland tumors develop in children and adolescents 1, 8, and mec is the most common malignancy 5, 9, 39, 40. Clear cell tumors of the oral mucosa, jaws and salivary glands may be either odontogenic, salivary gland, or metastatic in origin. Mucoepidermoid carcinoma of the hard palate sciencedirect. Adenoid cystic carcinoma is an uncommon, slow growing malignant salivary gland tumor that is characterized by wide local infiltration, perineural spread. Patient had noticed ulceration over the surface of the growth 15 days prior to seeking our opinion. Mar 25, 2006 i had surgery to remove a mucoepidermoid carcinoma from my palate on august 10, 2010. Research of hard palate squamous cell carcinoma has been linked to carcinoma, palatal neoplasms, malignant squamous cell neoplasm, hard palate carcinoma, neoplasm metastasis. Mucoepidermoid carcinoma of minor salivary gland in buccal mucosa. Mucoepidermoid carcinoma, abbreviated mec, the is the most common malignant neoplasm of the salivary gland.
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